Oral Biosci Med 1 (2004), No. 2 7. July 2004
Oral Biosci Med 1 (2004), No. 2 (07.07.2004)
Whole Saliva Flow Rates and Saliva Proteins in Patients with Burning Mouth Syndrome
Bez, Cristina/Uglietti, Daniela/Demarosi, Federica/Lodi, Giovanni/Sardella, Andrea/Viscardi, Sonia/Carrassi, Antonio
The aim of this study was to compare the amount of resting and stimulated whole saliva flow, the concentration of total salivary protein and the molecular weight profile of salivary proteins in patients suffering from burning mouth syndrome (BMS) with those in a control group.
The study group consisted of 12 BMS patients; 11 subjects not suffering from burning mouth sensation were enrolled as controls. Resting and stimulated whole saliva flow rates were evaluated by spitting method; the amount of salivary protein was estimated using the LP-200 spectrophotometer and a total protein kit (Sigma 690-A) whereas their molecular weight profile was investigated using the sodium dodecylsulfate-polyacrylamide gel electrophoresis system (SDS-PAGE).
No statistical differences were found between BMS patients and controls with respect to the flow rates of whole saliva, its protein concentration, or the electrophoretic profile of the salivary proteins.
Keywords: burning mouth syndrome, saliva, spectrophotometer analysis, electrophoresis