Oral Biosciences & Medicine
Oral Biosci Med 2 (2005), No. 4     27. Jan. 2006
Oral Biosci Med 1 (2004), No. 2  (07.07.2004)

Page 145-148

Maxillary Osteonecrosis in Visceral Leishmaniasis: a Case Report
Colella, Giuseppe/Borriello, Carlo/Scully, Crispian
Visceral Leishmaniasis is a vector-borne systemic parasitic infection found in many areas of the world. Typically, Leishmaniasis manifests with fever, hepatosplenomegaly, and pancytopenia. Oral lesions are uncommon. Definitive diagnosis still relies on the demonstration of the Leishmania parasite in tissues, although molecular methods appear promising as a non-invasive diagnostic tool. Pentavalent antimonial compounds remain the mainstay of treatment worldwide, but lipid formulations of amphotericin B, and more recently miltefosine, an oral active agent, have been introduced as antileishmanial treatment. We report a patient with visceral Leishmaniasis, who presented with the rare complication of maxillary osteonecrosis.

Keywords: oral, Leishmaniasis, bone, tropical infection